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The typical patient for this type of injury is a young individual that had no previous issues with the knee, but during activity got a twist to the knee or even just standing up from a sitting position got sudden onset of significant pain to one side of the knee

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This in turn leads to excessive storage of underutilized glucose in the liver (glycogenesis), the potential for developing fatty liver (ie, nonalcoholic steatohepatitis), and conversion of excess carbohydrates to fatty acids and triglycerides, with subsequent storage in adipose tissue